ICD-10-CM Book 2024 Edition

Chapters  /  Chapter 2  /  C15-C26

Malignant neoplasms of digestive organs (C15-C26)

Excludes1: Kaposi's sarcoma of gastrointestinal sites (C46.4)
Excludes2: gastrointestinal stromal tumors (C49.A-)
C15 Malignant neoplasm of esophagus
UseAdditionalCode code to identify:
alcohol abuse and dependence (F10.-)
C15.3 Malignant neoplasm of upper third of esophagus
C15.4 Malignant neoplasm of middle third of esophagus
C15.5 Malignant neoplasm of lower third of esophagus
Excludes1 malignant neoplasm of cardio-esophageal junction (C16.0)
C15.8 Malignant neoplasm of overlapping sites of esophagus
C15.9 Malignant neoplasm of esophagus, unspecified
C16 Malignant neoplasm of stomach
UseAdditionalCode code to identify:
alcohol abuse and dependence (F10.-)
Excludes2 malignant carcinoid tumor of the stomach (C7A.092)
C16.0 Malignant neoplasm of cardia
Malignant neoplasm of cardiac orifice
Malignant neoplasm of cardio-esophageal junction
Malignant neoplasm of esophagus and stomach
Malignant neoplasm of gastro-esophageal junction
C16.1 Malignant neoplasm of fundus of stomach
C16.2 Malignant neoplasm of body of stomach
C16.3 Malignant neoplasm of pyloric antrum
Malignant neoplasm of gastric antrum
C16.4 Malignant neoplasm of pylorus
Malignant neoplasm of prepylorus
Malignant neoplasm of pyloric canal
C16.5 Malignant neoplasm of lesser curvature of stomach, unspecified
Malignant neoplasm of lesser curvature of stomach, not classifiable to C16.1-C16.4
C16.6 Malignant neoplasm of greater curvature of stomach, unspecified
Malignant neoplasm of greater curvature of stomach, not classifiable to C16.0-C16.4
C16.8 Malignant neoplasm of overlapping sites of stomach
C16.9 Malignant neoplasm of stomach, unspecified
Gastric cancer NOS
C17 Malignant neoplasm of small intestine
Excludes1 malignant carcinoid tumors of the small intestine (C7A.01)
C17.0 Malignant neoplasm of duodenum
C17.1 Malignant neoplasm of jejunum
C17.2 Malignant neoplasm of ileum
Excludes1 malignant neoplasm of ileocecal valve (C18.0)
C17.3 Meckel's diverticulum, malignant
Excludes1 Meckel's diverticulum, congenital (Q43.0)
C17.8 Malignant neoplasm of overlapping sites of small intestine
C17.9 Malignant neoplasm of small intestine, unspecified
C18 Malignant neoplasm of colon
Excludes1 malignant carcinoid tumors of the colon (C7A.02-)
C18.0 Malignant neoplasm of cecum
Malignant neoplasm of ileocecal valve
C18.1 Malignant neoplasm of appendix
C18.2 Malignant neoplasm of ascending colon
C18.3 Malignant neoplasm of hepatic flexure
C18.4 Malignant neoplasm of transverse colon
C18.5 Malignant neoplasm of splenic flexure
C18.6 Malignant neoplasm of descending colon
C18.7 Malignant neoplasm of sigmoid colon
Malignant neoplasm of sigmoid (flexure)
Excludes1 malignant neoplasm of rectosigmoid junction (C19)
C18.8 Malignant neoplasm of overlapping sites of colon
C18.9 Malignant neoplasm of colon, unspecified
Malignant neoplasm of large intestine NOS
C19 Malignant neoplasm of rectosigmoid junction
Malignant neoplasm of colon with rectum
Malignant neoplasm of rectosigmoid (colon)
Excludes1 malignant carcinoid tumors of the colon (C7A.02-)
C20 Malignant neoplasm of rectum
Malignant neoplasm of rectal ampulla
Excludes1 malignant carcinoid tumor of the rectum (C7A.026)
C21 Malignant neoplasm of anus and anal canal
Excludes2 malignant carcinoid tumors of the colon (C7A.02-)
malignant melanoma of anal margin (C43.51)
malignant melanoma of anal skin (C43.51)
malignant melanoma of perianal skin (C43.51)
other and unspecified malignant neoplasm of anal margin (C44.500, C44.510, C44.520, C44.590)
other and unspecified malignant neoplasm of anal skin (C44.500, C44.510, C44.520, C44.590)
other and unspecified malignant neoplasm of perianal skin (C44.500, C44.510, C44.520, C44.590)
C21.0 Malignant neoplasm of anus, unspecified
C21.1 Malignant neoplasm of anal canal
Malignant neoplasm of anal sphincter
C21.2 Malignant neoplasm of cloacogenic zone
C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal
Malignant neoplasm of anorectal junction
Malignant neoplasm of anorectum
Primary malignant neoplasm of two or more contiguous sites of rectum, anus and anal canal
C22 Malignant neoplasm of liver and intrahepatic bile ducts
Excludes1 malignant neoplasm of biliary tract NOS (C24.9)
secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
UseAdditionalCode code to identify:
alcohol abuse and dependence (F10.-)
hepatitis B (B16.-, B18.0-B18.1)
hepatitis C (B17.1-, B18.2)
C22.0 Liver cell carcinoma
Hepatocellular carcinoma
Hepatoma
C22.1 Intrahepatic bile duct carcinoma
Cholangiocarcinoma
Excludes1 malignant neoplasm of hepatic duct (C24.0)
C22.2 Hepatoblastoma
C22.3 Angiosarcoma of liver
Kupffer cell sarcoma
C22.4 Other sarcomas of liver
C22.7 Other specified carcinomas of liver
C22.8 Malignant neoplasm of liver, primary, unspecified as to type
C22.9 Malignant neoplasm of liver, not specified as primary or secondary
C23 Malignant neoplasm of gallbladder
C24 Malignant neoplasm of other and unspecified parts of biliary tract
Excludes1 malignant neoplasm of intrahepatic bile duct (C22.1)
C24.0 Malignant neoplasm of extrahepatic bile duct
Malignant neoplasm of biliary duct or passage NOS
Malignant neoplasm of common bile duct
Malignant neoplasm of cystic duct
Malignant neoplasm of hepatic duct
C24.1 Malignant neoplasm of ampulla of Vater
C24.8 Malignant neoplasm of overlapping sites of biliary tract
Malignant neoplasm involving both intrahepatic and extrahepatic bile ducts
Primary malignant neoplasm of two or more contiguous sites of biliary tract
C24.9 Malignant neoplasm of biliary tract, unspecified
C25 Malignant neoplasm of pancreas
CodeAlso if applicable exocrine pancreatic insufficiency (K86.81)
UseAdditionalCode code to identify:
alcohol abuse and dependence (F10.-)
C25.0 Malignant neoplasm of head of pancreas
C25.1 Malignant neoplasm of body of pancreas
C25.2 Malignant neoplasm of tail of pancreas
C25.3 Malignant neoplasm of pancreatic duct
C25.4 Malignant neoplasm of endocrine pancreas
Malignant neoplasm of islets of Langerhans
UseAdditionalCode code to identify any functional activity.
C25.7 Malignant neoplasm of other parts of pancreas
Malignant neoplasm of neck of pancreas
C25.8 Malignant neoplasm of overlapping sites of pancreas
C25.9 Malignant neoplasm of pancreas, unspecified
C26 Malignant neoplasm of other and ill-defined digestive organs
Excludes1 malignant neoplasm of peritoneum and retroperitoneum (C48.-)
C26.0 Malignant neoplasm of intestinal tract, part unspecified
Malignant neoplasm of intestine NOS
C26.1 Malignant neoplasm of spleen
Excludes1 Hodgkin lymphoma (C81.-)
non-Hodgkin lymphoma (C82-C85)
C26.9 Malignant neoplasm of ill-defined sites within the digestive system
Malignant neoplasm of alimentary canal or tract NOS
Malignant neoplasm of gastrointestinal tract NOS
Excludes1 malignant neoplasm of abdominal NOS (C76.2)
malignant neoplasm of intra-abdominal NOS (C76.2)