E16 | 
		 | 
		Other disorders of pancreatic internal secretion   | 
	
 |  | 
	
		 E16.0 | 
		  | 
		Drug-induced hypoglycemia without coma | 
	 
	
		 |  | 
		
	
		| Excludes1 | 
		diabetes with hypoglycemia without coma (E09.649)
  | 
	 
	
		| UseAdditionalCode | 
		code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  | 
	 
	
		| UseAdditionalCode | 
		code for hypoglycemia level, if applicable (E16.A-)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 E16.1 | 
		  | 
		Other hypoglycemia | 
	 
	
		 |  | 
		
| Functional hyperinsulinism |  | Functional nonhyperinsulinemic hypoglycemia |  | Hyperinsulinism NOS |  | Hyperplasia of pancreatic islet beta cells NOS |  	
		| UseAdditionalCode | 
		code for hypoglycemia level, if applicable (E16.A-)
  | 
	 
	
		| Excludes1 | 
		diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649) hypoglycemia in infant of diabetic mother (P70.1) neonatal hypoglycemia (P70.4)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 E16.2 | 
		  | 
		Hypoglycemia, unspecified | 
	 
	
		 |  | 
		
 | 
	   | 
 |  | 
	
		 E16.3 | 
		  | 
		Increased secretion of glucagon | 
	 
	
		 |  | 
		
| Hyperplasia of pancreatic endocrine cells with glucagon excess |   
 | 
	   | 
 |  | 
	
		 E16.4 | 
		  | 
		Increased secretion of gastrin | 
	 
	
		 |  | 
		
| Hypergastrinemia |  | Hyperplasia of pancreatic endocrine cells with gastrin excess |  | Zollinger-Ellison syndrome |   
 | 
	   | 
 |  | 
	
		 E16.8 | 
		  | 
		Other specified disorders of pancreatic internal secretion | 
	 
	
		 |  | 
		
| Increased secretion from endocrine pancreas of growth hormone-releasing hormone |  | Increased secretion from endocrine pancreas of pancreatic polypeptide |  | Increased secretion from endocrine pancreas of somatostatin |  | Increased secretion from endocrine pancreas of vasoactive-intestinal polypeptide |   
 | 
	   | 
 |  | 
	
		 E16.9 | 
		  | 
		Disorder of pancreatic internal secretion, unspecified | 
	 
	
		 |  | 
		
| Islet-cell hyperplasia NOS |  | Pancreatic endocrine cell hyperplasia NOS |   
 | 
	   | 
 |  | 
	
		 E16.A | 
		 | 
		Hypoglycemia level | 
	 
 |  | 
	
		 E16.A1 | 
		  | 
		Hypoglycemia level 1 | 
	 
	
		 |  | 
		
| Decreased blood glucose level 1 |   
 | 
	   |   |  | 
	
		 E16.A2 | 
		  | 
		Hypoglycemia level 2 | 
	 
	
		 |  | 
		
| Decreased blood glucose level 2 |   
 | 
	   |   |  | 
	
		 E16.A3 | 
		  | 
		Hypoglycemia level 3 | 
	 
	
		 |  | 
		
| Decreased blood glucose level 3 |   
 | 
	   |    |