M35 | 
		  | 
		Other systemic involvement of connective tissue   | 
	
	
		 |  | 
		
	
		| Excludes1 | 
		reactive perforating collagenosis (L87.1)
  | 
	 
 
 | 
	
 |  | 
	
		 M35.0 | 
		  | 
		Sjögren syndrome | 
	 
	
		 |  | 
		
| Sicca syndrome |  	
		| UseAdditionalCode | 
		code to identify associated manifestations
  | 
	 
	
		| Excludes1 | 
		dry mouth, unspecified (R68.2)
  | 
	 
 
 | 
	  |  | 
	
		 M35.00 | 
		 | 
		Sjögren syndrome, unspecified | 
	 
  |   |  | 
	
		 M35.01 | 
		 | 
		Sjögren syndrome with keratoconjunctivitis | 
	 
  |   |  | 
	
		 M35.02 | 
		 | 
		Sjögren syndrome with lung involvement | 
	 
  |   |  | 
	
		 M35.03 | 
		 | 
		Sjögren syndrome with myopathy | 
	 
  |   |  | 
	
		 M35.04 | 
		  | 
		Sjögren syndrome with tubulo-interstitial nephropathy | 
	 
	
		 |  | 
		
| Renal tubular acidosis in sicca syndrome |   
 | 
	   |   |  | 
	
		 M35.05 | 
		 | 
		Sjögren syndrome with inflammatory arthritis | 
	 
  |   |  | 
	
		 M35.06 | 
		 | 
		Sjögren syndrome with peripheral nervous system involvement | 
	 
  |   |  | 
	
		 M35.07 | 
		 | 
		Sjögren syndrome with central nervous system involvement | 
	 
  |   |  | 
	
		 M35.08 | 
		 | 
		Sjögren syndrome with gastrointestinal involvement | 
	 
  |   |  | 
	
		 M35.0A | 
		 | 
		Sjögren syndrome with glomerular disease | 
	 
  |   |  | 
	
		 M35.0B | 
		 | 
		Sjögren syndrome with vasculitis | 
	 
  |   |  | 
	
		 M35.0C | 
		 | 
		Sjögren syndrome with dental involvement | 
	 
  |   |  | 
	
		 M35.09 | 
		 | 
		Sjögren syndrome with other organ involvement | 
	 
  |    | 
 |  | 
	
		 M35.1 | 
		  | 
		Other overlap syndromes | 
	 
	
		 |  | 
		
| Mixed connective tissue disease |  	
		| Excludes1 | 
		polyangiitis overlap syndrome (M30.8)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 M35.2 | 
		 | 
		Behçet's disease | 
	 
  | 
 |  | 
	
		 M35.3 | 
		  | 
		Polymyalgia rheumatica | 
	 
	
		 |  | 
		
	
		| Excludes1 | 
		polymyalgia rheumatica with giant cell arteritis (M31.5)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 M35.4 | 
		 | 
		Diffuse (eosinophilic) fasciitis | 
	 
  | 
 |  | 
	
		 M35.5 | 
		 | 
		Multifocal fibrosclerosis | 
	 
  | 
 |  | 
	
		 M35.6 | 
		  | 
		Relapsing panniculitis [Weber-Christian] | 
	 
	
		 |  | 
		
	
		| Excludes1 | 
		lupus panniculitis (L93.2) panniculitis NOS (M79.3-)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 M35.7 | 
		  | 
		Hypermobility syndrome | 
	 
	
		 |  | 
		
| Familial ligamentous laxity |  	
		| Excludes1 | 
		ligamentous laxity, NOS (M24.2-)
  | 
	 
	
		| Excludes2 | 
		Ehlers-Danlos syndromes (Q79.6-)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 M35.8 | 
		 | 
		Other specified systemic involvement of connective tissue | 
	 
 |  | 
	
		 M35.81 | 
		  | 
		Multisystem inflammatory syndrome | 
	 
	
		 |  | 
		
| MIS-A |  | MIS-C |  | Multisystem inflammatory syndrome in adults |  | Multisystem inflammatory syndrome in children |  | Pediatric inflammatory multisystem syndrome |  | PIMS |  	
		| CodeFirst | 
		, if applicable, COVID-19 (U07.1)
  | 
	 
	
		| CodeAlso | 
		any associated complications such as: acute hepatic failure (K72.0-) acute kidney failure (N17.-) acute myocarditis (I40.-) acute respiratory distress syndrome (J80) cardiac arrhythmia (I47-I49.-) pneumonia due to COVID-19 (J12.82) severe sepsis (R65.2-) viral cardiomyopathy (B33.24) viral pericarditis (B33.23)
  | 
	 
	
		| UseAdditionalCode | 
		code, if applicable, for: exposure to COVID-19 or SARS-CoV-2 infection (Z20.822) personal history of COVID-19 (Z86.16) post COVID-19 condition (U09.9)
  | 
	 
 
 | 
	   |   |  | 
	
		 M35.89 | 
		 | 
		Other specified systemic involvement of connective tissue | 
	 
  |    | 
 |  | 
	
		 M35.9 | 
		  | 
		Systemic involvement of connective tissue, unspecified | 
	 
	
		 |  | 
		
| Autoimmune disease (systemic) NOS |  | Collagen (vascular) disease NOS |   
 | 
	   |