ICD-10-CM Book 2026 Edition

Chapters  /  Chapter 6  /  G35-G37

Demyelinating diseases of the central nervous system (G35-G37)

G35 Multiple sclerosis
G35.A Relapsing-remitting multiple sclerosis
Exclude1: demyelinating disease of central nervous system, unspecified (G37.9)
G35.B Primary progressive multiple sclerosis
G35.B0 Primary progressive multiple sclerosis, unspecified
G35.B1 Active primary progressive multiple sclerosis
Primary progressive multiple sclerosis with evidence of inflammatory disease activity
G35.B2 Non-active primary progressive multiple sclerosis
Primary progressive multiple sclerosis without evidence of inflammatory disease activity
G35.C Secondary progressive multiple sclerosis
G35.C0 Secondary progressive multiple sclerosis, unspecified
G35.C1 Active secondary progressive multiple sclerosis
Secondary progressive multiple sclerosis with evidence of inflammatory disease activity
G35.C2 Non-active secondary progressive multiple sclerosis
Secondary progressive multiple sclerosis without evidence of inflammatory disease activity
G35.D Multiple sclerosis, unspecified
Disseminated multiple sclerosis
Generalized multiple sclerosis
Multiple sclerosis NOS
Multiple sclerosis of brain stem
Multiple sclerosis of cord
G36 Other acute disseminated demyelination
Excludes1 postinfectious encephalitis and encephalomyelitis NOS (G04.01)
G36.0 Neuromyelitis optica [Devic]
Demyelination in optic neuritis
Excludes1 optic neuritis NOS (H46)
G36.1 Acute and subacute hemorrhagic leukoencephalitis [Hurst]
G36.8 Other specified acute disseminated demyelination
G36.9 Acute disseminated demyelination, unspecified
G37 Other demyelinating diseases of central nervous system
G37.0 Diffuse sclerosis of central nervous system
Periaxial encephalitis
Schilder's disease
Excludes1 X linked adrenoleukodystrophy (E71.52-)
G37.1 Central demyelination of corpus callosum
G37.2 Central pontine myelinolysis
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
Acute transverse myelitis NOS
Acute transverse myelopathy
Excludes1 acute flaccid myelitis (G04.82)
multiple sclerosis (G35-)
neuromyelitis optica [Devic] (G36.0)
G37.4 Subacute necrotizing myelitis of central nervous system
G37.5 Concentric sclerosis [Balo] of central nervous system
G37.8 Other specified demyelinating diseases of central nervous system
G37.81 Myelin oligodendrocyte glycoprotein antibody disease
MOG antibody disease
CodeAlso associated manifestations, if known, such as:
noninfectious acute disseminated encephalomyelitis (G04.81)
neuromyelitis optica (G36.0)
G37.89 Other specified demyelinating diseases of central nervous system
G37.9 Demyelinating disease of central nervous system, unspecified
Clinically isolated syndromes