ICD-10-CM Book 2026 Edition

Chapters  /  Chapter 2  /  C15-C26  /  C21
C21 Malignant neoplasm of anus and anal canal
Excludes2 malignant carcinoid tumors of the colon (C7A.02-)
malignant melanoma of anal margin (C43.51)
malignant melanoma of anal skin (C43.51)
malignant melanoma of perianal skin (C43.51)
other and unspecified malignant neoplasm of anal margin (C44.500, C44.510, C44.520, C44.590)
other and unspecified malignant neoplasm of anal skin (C44.500, C44.510, C44.520, C44.590)
other and unspecified malignant neoplasm of perianal skin (C44.500, C44.510, C44.520, C44.590)
C21.0 Malignant neoplasm of anus, unspecified
C21.1 Malignant neoplasm of anal canal
Malignant neoplasm of anal sphincter
C21.2 Malignant neoplasm of cloacogenic zone
C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal
Malignant neoplasm of anorectal junction
Malignant neoplasm of anorectum
Primary malignant neoplasm of two or more contiguous sites of rectum, anus and anal canal