ICD-10-CM Book 2024 Edition

Chapters  /  Chapter 4  /  E70-E88  /  E88
E88 Other and unspecified metabolic disorders
UseAdditionalCode codes for associated conditions
Excludes1 histiocytosis X (chronic) (C96.6)
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
Excludes1 monoclonal gammopathy (of undetermined significance) (D47.2)
polyclonal hypergammaglobulinemia (D89.0)
Waldenström macroglobulinemia (C88.0)
Excludes2 disorder of lipoprotein metabolism (E78.-)
E88.01 Alpha-1-antitrypsin deficiency
AAT deficiency
E88.02 Plasminogen deficiency
Dysplasminogenemia
Hypoplasminogenemia
Type 1 plasminogen deficiency
Type 2 plasminogen deficiency
CodeAlso , if applicable, ligneous conjunctivitis (H10.51)
UseAdditionalCode code for associated findings, such as:
hydrocephalus (G91.4)
otitis media (H67.-)
respiratory disorder related to plasminogen deficiency (J99)
E88.09 Other disorders of plasma-protein metabolism, not elsewhere classified
Bisalbuminemia
E88.1 Lipodystrophy, not elsewhere classified
Lipodystrophy NOS
Excludes1 Whipple's disease (K90.81)
E88.2 Lipomatosis, not elsewhere classified
Lipomatosis NOS
Lipomatosis (Check) dolorosa [Dercum]
E88.3 Tumor lysis syndrome
Tumor lysis syndrome (spontaneous)
Tumor lysis syndrome following antineoplastic drug chemotherapy
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T45.1X5)
E88.4 Mitochondrial metabolism disorders
Excludes1 disorders of pyruvate metabolism (E74.4)
Kearns-Sayre syndrome (H49.81)
Leber's disease (H47.22)
Leigh's encephalopathy (G31.82)
Mitochondrial myopathy, NEC (G71.3)
Reye's syndrome (G93.7)
E88.40 Mitochondrial metabolism disorder, unspecified
E88.41 MELAS syndrome
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes
E88.42 MERRF syndrome
Myoclonic epilepsy associated with ragged-red fibers
CodeAlso progressive myoclonic epilepsy (G40.3-)
E88.43 Disorders of mitochondrial tRNA synthetases
E88.49 Other mitochondrial metabolism disorders
E88.8 Other specified metabolic disorders
E88.81 Metabolic syndrome and other insulin resistance
UseAdditionalCode codes for associated manifestations, such as:
obesity (E66.-)
E88.810 Metabolic syndrome
Dysmetabolic syndrome
E88.811 Insulin resistance syndrome, Type A
E88.818 Other insulin resistance
Insulin resistance syndrome, Type B
E88.819 Insulin resistance, unspecified
E88.89 Other specified metabolic disorders
Launois-Bensaude adenolipomatosis
Excludes1 adult pulmonary Langerhans cell histiocytosis (J84.82)
E88.9 Metabolic disorder, unspecified
E88.A Wasting disease (syndrome) due to underlying condition
Cachexia due to underlying condition
CodeFirst underlying condition
Excludes1 cachexia NOS (R64)
nutritional marasmus (E41)
Excludes2 failure to thrive (R62.51, R62.7)