ICD-10-CM Book 2024 Edition

Chapters  /  Chapter 3  /  D70-D77

Other disorders of blood and blood-forming organs (D70-D77)

D70 Neutropenia
Includes agranulocytosis
decreased absolute neurophile count (ANC)
UseAdditionalCode code for any associated:
fever (R50.81)
CodeAlso , if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)
Excludes1 neutropenic splenomegaly (D73.81)
transient neonatal neutropenia (P61.5)
D70.0 Congenital agranulocytosis
Congenital neutropenia
Infantile genetic agranulocytosis
Kostmann's disease
D70.1 Agranulocytosis secondary to cancer chemotherapy
CodeAlso underlying neoplasm
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T45.1X5)
D70.2 Other drug-induced agranulocytosis
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
D70.3 Neutropenia due to infection
D70.4 Cyclic neutropenia
Cyclic hematopoiesis
Periodic neutropenia
D70.8 Other neutropenia
D70.9 Neutropenia, unspecified
D71 Functional disorders of polymorphonuclear neutrophils
Cell membrane receptor complex [CR3] defect
Chronic (childhood) granulomatous disease
Congenital dysphagocytosis
Progressive septic granulomatosis
D72 Other disorders of white blood cells
Excludes1 basophilia (D72.824)
immunity disorders (D80-D89)
neutropenia (D70)
preleukemia (syndrome) (D46.9)
D72.0 Genetic anomalies of leukocytes
Alder (granulation) (granulocyte) anomaly
Alder syndrome
Hereditary leukocytic hypersegmentation
Hereditary leukocytic hyposegmentation
Hereditary leukomelanopathy
May-Hegglin (granulation) (granulocyte) anomaly
May-Hegglin syndrome
Pelger-Huët (granulation) (granulocyte) anomaly
Pelger-Huët syndrome
Excludes1 Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)
D72.1 Eosinophilia
Excludes2 Löffler's syndrome (J82.89)
pulmonary eosinophilia (J82.-)
D72.10 Eosinophilia, unspecified
D72.11 Hypereosinophilic syndrome [HES]
D72.110 Idiopathic hypereosinophilic syndrome [IHES]
D72.111 Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
Lymphocyte variant hypereosinophilia
CodeAlso , if applicable, any associated lymphocytic neoplastic disorder
D72.118 Other hypereosinophilic syndrome
Episodic angioedema with eosinophilia
Gleich's syndrome
D72.119 Hypereosinophilic syndrome [HES], unspecified
D72.12 Drug rash with eosinophilia and systemic symptoms syndrome
DRESS syndrome
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
D72.18 Eosinophilia in diseases classified elsewhere
CodeFirst underlying disease, such as:
chronic myelomonocytic leukemia (C93.1-)
D72.19 Other eosinophilia
Familial eosinophilia
Hereditary eosinophilia
D72.8 Other specified disorders of white blood cells
Excludes1 leukemia (C91-C95)
D72.81 Decreased white blood cell count
Excludes1 neutropenia (D70.-)
D72.810 Lymphocytopenia
Decreased lymphocytes
D72.818 Other decreased white blood cell count
Basophilic leukopenia
Eosinophilic leukopenia
Monocytopenia
Other decreased leukocytes
Plasmacytopenia
D72.819 Decreased white blood cell count, unspecified
Decreased leukocytes, unspecified
Leukocytopenia, unspecified
Leukopenia
Excludes1 malignant leukopenia (D70.9)
D72.82 Elevated white blood cell count
Excludes1 eosinophilia (D72.1)
D72.820 Lymphocytosis (symptomatic)
Elevated lymphocytes
D72.821 Monocytosis (symptomatic)
Excludes1 infectious mononucleosis (B27.-)
D72.822 Plasmacytosis
D72.823 Leukemoid reaction
Basophilic leukemoid reaction
Leukemoid reaction NOS
Lymphocytic leukemoid reaction
Monocytic leukemoid reaction
Myelocytic leukemoid reaction
Neutrophilic leukemoid reaction
D72.824 Basophilia
D72.825 Bandemia
Bandemia without diagnosis of specific infection
Excludes1 confirmed infection - code to infection
leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)
D72.828 Other elevated white blood cell count
D72.829 Elevated white blood cell count, unspecified
Elevated leukocytes, unspecified
Leukocytosis, unspecified
D72.89 Other specified disorders of white blood cells
Abnormality of white blood cells NEC
D72.9 Disorder of white blood cells, unspecified
Abnormal leukocyte differential NOS
D73 Diseases of spleen
D73.0 Hyposplenism
Atrophy of spleen
Excludes1 asplenia (congenital) (Q89.01)
postsurgical absence of spleen (Z90.81)
D73.1 Hypersplenism
Excludes1 neutropenic splenomegaly (D73.81)
primary splenic neutropenia (D73.81)
splenitis, splenomegaly in late syphilis (A52.79)
splenitis, splenomegaly in tuberculosis (A18.85)
splenomegaly NOS (R16.1)
splenomegaly congenital (Q89.0)
D73.2 Chronic congestive splenomegaly
D73.3 Abscess of spleen
D73.4 Cyst of spleen
D73.5 Infarction of spleen
Splenic rupture, nontraumatic
Torsion of spleen
Excludes1 rupture of spleen due to Plasmodium vivax malaria (B51.0)
traumatic rupture of spleen (S36.03-)
D73.8 Other diseases of spleen
D73.81 Neutropenic splenomegaly
Werner-Schultz disease
D73.89 Other diseases of spleen
Fibrosis of spleen NOS
Perisplenitis
Splenitis NOS
D73.9 Disease of spleen, unspecified
D74 Methemoglobinemia
D74.0 Congenital methemoglobinemia
Congenital NADH-methemoglobin reductase deficiency
Hemoglobin-M [Hb-M] disease
Methemoglobinemia, hereditary
D74.8 Other methemoglobinemias
Acquired methemoglobinemia (with sulfhemoglobinemia)
Toxic methemoglobinemia
D74.9 Methemoglobinemia, unspecified
D75 Other and unspecified diseases of blood and blood-forming organs
Excludes2 acute lymphadenitis (L04.-)
chronic lymphadenitis (I88.1)
enlarged lymph nodes (R59.-)
hypergammaglobulinemia NOS (D89.2)
lymphadenitis NOS (I88.9)
mesenteric lymphadenitis (acute) (chronic) (I88.0)
D75.0 Familial erythrocytosis
Benign polycythemia
Familial polycythemia
Excludes1 hereditary ovalocytosis (D58.1)
D75.1 Secondary polycythemia
Acquired polycythemia
Emotional polycythemia
Erythrocytosis NOS
Hypoxemic polycythemia
Nephrogenous polycythemia
Polycythemia due to erythropoietin
Polycythemia due to fall in plasma volume
Polycythemia due to high altitude
Polycythemia due to stress
Polycythemia NOS
Relative polycythemia
Excludes1 polycythemia neonatorum (P61.1)
polycythemia vera (D45)
D75.8 Other specified diseases of blood and blood-forming organs
D75.81 Myelofibrosis
Myelofibrosis NOS
Secondary myelofibrosis NOS
CodeFirst the underlying disorder, such as:
malignant neoplasm of breast (C50.-)
UseAdditionalCode code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T45.1X5)
Excludes1 acute myelofibrosis (C94.4-)
idiopathic myelofibrosis (D47.1)
leukoerythroblastic anemia (D61.82)
myelofibrosis with myeloid metaplasia (D47.4)
myelophthisic anemia (D61.82)
myelophthisis (D61.82)
primary myelofibrosis (D47.1)
nonPrimary Yes
D75.82 Heparin induced thrombocytopenia (HIT)
UseAdditionalCode code, if applicable, for adverse effect of heparin (T45.515-)
D75.821 Non-immune heparin-induced thrombocytopenia
Non-immune HIT
Type 1 heparin-induced thrombocytopenia
D75.822 Immune-mediated heparin-induced thrombocytopenia
Immune-mediated HIT
Type 2 heparin-induced thrombocytopenia
D75.828 Other heparin-induced thrombocytopenia syndrome
Autoimmune heparin-induced thrombocytopenia syndrome
Delayed-onset heparin-induced thrombocytopenia
Persisting heparin-induced thrombocytopenia
D75.829 Heparin-induced thrombocytopenia, unspecified
D75.83 Thrombocytosis
Excludes2 essential thrombocythemia (D47.3)
D75.838 Other thrombocytosis
Reactive thrombocytosis
Secondary thrombocytosis
CodeAlso underlying condition, if known and applicable
D75.839 Thrombocytosis, unspecified
Thrombocythemia NOS
Thrombocytosis NOS
D75.84 Other platelet-activating anti-PF4 disorders
Spontaneous heparin-induced thrombocytopenia syndrome (without heparin exposure)
Thrombosis with thrombocytopenia syndrome
Vaccine-induced thrombotic thrombocytopenia
UseAdditionalCode code, if applicable, for adverse effect of other viral vaccine (T50.B95-)
D75.89 Other specified diseases of blood and blood-forming organs
D75.9 Disease of blood and blood-forming organs, unspecified
D75.A Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
Excludes1 glucose-6-phosphate dehydrogenase (G6PD) deficiency with anemia (D55.0)
D76 Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
Excludes1 (Abt-) Letterer-Siwe disease (C96.0)
eosinophilic granuloma (C96.6)
Hand-Schüller-Christian disease (C96.5)
histiocytic medullary reticulosis (C96.9)
histiocytic sarcoma (C96.A)
histiocytosis X, multifocal (C96.5)
histiocytosis X, unifocal (C96.6)
Langerhans-cell histiocytosis, multifocal (C96.5)
Langerhans-cell histiocytosis NOS (C96.6)
Langerhans-cell histiocytosis, unifocal (C96.6)
leukemic reticuloendotheliosis (C91.4-)
lipomelanotic reticulosis (I89.8)
malignant histiocytosis (C96.A)
malignant reticulosis (C86.0)
nonlipid reticuloendotheliosis (C96.0)
D76.1 Hemophagocytic lymphohistiocytosis
Familial hemophagocytic reticulosis
Histiocytoses of mononuclear phagocytes
D76.2 Hemophagocytic syndrome, infection-associated
UseAdditionalCode code to identify infectious agent or disease.
D76.3 Other histiocytosis syndromes
Reticulohistiocytoma (giant-cell)
Sinus histiocytosis with massive lymphadenopathy
Xanthogranuloma
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
CodeFirst underlying disease, such as:
amyloidosis (E85.-)
congenital early syphilis (A50.0-)
echinococcosis (B67.0-B67.9)
malaria (B50.0-B54)
schistosomiasis [bilharziasis] (B65.0-B65.9)
vitamin C deficiency (E54)
Excludes1 rupture of spleen due to Plasmodium vivax malaria (B51.0)
splenitis, splenomegaly in late syphilis (A52.79)
splenitis, splenomegaly in tuberculosis (A18.85)
nonPrimary Yes