|  D68 |  | Other coagulation defects   | 
	
		|  |  | 
	
		| Excludes1 | abnormal coagulation profile NOS (R79.1) 
 |  
		| Excludes2 | coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)
 
 |  | 
|  |  | 
	
		|  D68.0 |  | Von Willebrand disease |  
		|  |  | 
	
		| Excludes1 | capillary fragility (hereditary) (D69.8) factor VIII deficiency NOS (D66)
 factor VIII deficiency with functional defect (D66)
 
 |  |  |  |  | 
	
		|  D68.00 |  | Von Willebrand disease, unspecified |  |  |  |  | 
	
		|  D68.01 |  | Von Willebrand disease, type 1 |  
		|  |  | 
| Partial quantitative deficiency of von Willebrand factor |  | Type 1C von Willebrand disease |  |  |  |  |  | 
	
		|  D68.02 |  | Von Willebrand disease, type 2 |  
		|  |  | 
| Qualitative defects of von Willebrand factor |  |  |  |  | 
	
		|  D68.020 |  | Von Willebrand disease, type 2A |  
		|  |  | 
| Qualitative defects of von Willebrand factor with decreased platelet adhesion and selective deficiency of high-molecular-weight multimers |  |  |  |  |  | 
	
		|  D68.021 |  | Von Willebrand disease, type 2B |  
		|  |  | 
| Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss |  | Qualitative defects of von Willebrand factor with hyper-adhesive forms |  | Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb |  |  |  |  |  | 
	
		|  D68.022 |  | Von Willebrand disease, type 2M |  
		|  |  | 
| Qualitative defects of von Willebrand factor with defective platelet adhesion with a normal size distribution of von Willebrand factor multimers |  |  |  |  |  | 
	
		|  D68.023 |  | Von Willebrand disease, type 2N |  
		|  |  | 
| Qualitative defects of von Willebrand factor with defective von Willebrand factor to factor VIII binding |  | Qualitative defects of von Willebrand factor with markedly decreased affinity for factor VIII |  |  |  |  |  | 
	
		|  D68.029 |  | Von Willebrand disease, type 2, unspecified |  
		|  |  | 
| Qualitative defect in von Willebrand factor function, with no further subtyping |  |  |  |  |  |  | 
	
		|  D68.03 |  | Von Willebrand disease, type 3 |  
		|  |  | 
| (Near) complete absence of von Willebrand factor |  | Total quantitative deficiency of von Willebrand factor |  |  |  |  |  | 
	
		|  D68.04 |  | Acquired von Willebrand disease |  
		|  |  | 
| Acquired von Willebrand syndrome |  |  |  |  |  | 
	
		|  D68.09 |  | Other von Willebrand disease |  
		|  |  | 
| Platelet-type von Willebrand disease |  | Pseudo-von Willebrand disease |  
		| CodeAlso | , if applicable, qualitative platelet defects (D69.1) 
 |  |  |  | 
|  |  | 
	
		|  D68.1 |  | Hereditary factor XI deficiency |  
		|  |  | 
| Hemophilia C |  | Plasma thromboplastin antecedent [PTA] deficiency |  | Rosenthal's disease |  |  | 
|  |  | 
	
		|  D68.2 |  | Hereditary deficiency of other clotting factors |  
		|  |  | 
| AC globulin deficiency |  | Congenital afibrinogenemia |  | Deficiency of factor I [fibrinogen] |  | Deficiency of factor II [prothrombin] |  | Deficiency of factor V [labile] |  | Deficiency of factor VII [stable] |  | Deficiency of factor X [Stuart-Prower] |  | Deficiency of factor XII [Hageman] |  | Deficiency of factor XIII [fibrin stabilizing] |  | Dysfibrinogenemia (congenital) |  | Hypoproconvertinemia |  | Owren's disease |  | Proaccelerin deficiency |  |  | 
|  |  | 
	
		|  D68.3 |  | Hemorrhagic disorder due to circulating anticoagulants |  |  |  | 
	
		|  D68.31 |  | Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors |  |  |  | 
	
		|  D68.311 |  | Acquired hemophilia |  
		|  |  | 
| Autoimmune hemophilia |  | Autoimmune inhibitors to clotting factors |  | Secondary hemophilia |  |  |  |  |  | 
	
		|  D68.312 |  | Antiphospholipid antibody with hemorrhagic disorder |  
		|  |  | 
| Lupus anticoagulant (LAC) with hemorrhagic disorder |  | Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder |  
		| Excludes1 | antiphospholipid antibody, finding without diagnosis (R76.0) lupus anticoagulant (LAC) finding without diagnosis (R76.0)
 systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
 
 |  
		| Excludes2 | antiphospholipid antibody syndrome (D68.61) antiphospholipid antibody with hypercoagulable state (D68.61)
 lupus anticoagulant (LAC) with hypercoagulable state (D68.62)
 systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62)
 
 |  |  |  |  |  | 
	
		|  D68.318 |  | Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors |  
		|  |  | 
| Antithromboplastinemia |  | Antithromboplastinogenemia |  | Hemorrhagic disorder due to intrinsic increase in antithrombin |  | Hemorrhagic disorder due to intrinsic increase in anti-VIIIa |  | Hemorrhagic disorder due to intrinsic increase in anti-IXa |  | Hemorrhagic disorder due to intrinsic increase in anti-XIa |  |  |  |  |  |  | 
	
		|  D68.32 |  | Hemorrhagic disorder due to extrinsic circulating anticoagulants |  
		|  |  | 
| Drug-induced hemorrhagic disorder |  | Hemorrhagic disorder due to increase in anti-IIa |  | Hemorrhagic disorder due to increase in anti-Xa |  | Hyperheparinemia |  
		| UseAdditionalCode | code for adverse effect, if applicable, to identify drug (T45.515, T45.525) 
 |  |  |  | 
|  |  | 
	
		|  D68.4 |  | Acquired coagulation factor deficiency |  
		|  |  | 
| Deficiency of coagulation factor due to liver disease |  | Deficiency of coagulation factor due to vitamin K deficiency |  
		| Excludes1 | vitamin K deficiency of newborn (P53) 
 |  |  | 
|  |  | 
	
		|  D68.5 |  | Primary thrombophilia |  
		|  |  | 
| Primary hypercoagulable states |  
		| Excludes1 | antiphospholipid syndrome (D68.61) lupus anticoagulant (D68.62)
 secondary activated protein C resistance (D68.69)
 secondary antiphospholipid antibody syndrome (D68.69)
 secondary lupus anticoagulant with hypercoagulable state (D68.69)
 secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
 systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
 systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
 thrombotic thrombocytopenic purpura (M31.19)
 
 |  |  |  |  | 
	
		|  D68.51 |  | Activated protein C resistance |  
		|  |  |  |  |  |  |  | 
	
		|  D68.52 |  | Prothrombin gene mutation |  |  |  |  | 
	
		|  D68.59 |  | Other primary thrombophilia |  
		|  |  | 
| Antithrombin III deficiency |  | Hypercoagulable state NOS |  | Primary hypercoagulable state NEC |  | Primary thrombophilia NEC |  | Protein C deficiency |  | Protein S deficiency |  | Thrombophilia NOS |  |  |  | 
|  |  | 
	
		|  D68.6 |  | Other thrombophilia |  
		|  |  | 
| Other hypercoagulable states |  
		| Excludes1 | diffuse or disseminated intravascular coagulation [DIC] (D65) heparin induced thrombocytopenia (HIT) (D75.82-)
 hyperhomocysteinemia (E72.11)
 
 |  |  |  |  | 
	
		|  D68.61 |  | Antiphospholipid syndrome |  
		|  |  | 
| Anticardiolipin syndrome |  | Antiphospholipid antibody syndrome |  
		| Excludes1 | anti-phospholipid antibody, finding without diagnosis (R76.0) 
 |  
		| Excludes2 | anti-phospholipid antibody with hemorrhagic disorder (D68.312) lupus anticoagulant syndrome (D68.62)
 
 |  |  |  |  |  | 
	
		|  D68.62 |  | Lupus anticoagulant syndrome |  
		|  |  | 
| Lupus anticoagulant |  | Presence of systemic lupus erythematosus [SLE] inhibitor |  
		| Excludes1 | lupus anticoagulant (LAC) finding without diagnosis (R76.0) 
 |  
		| Excludes2 | anticardiolipin syndrome (D68.61) antiphospholipid syndrome (D68.61)
 lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312)
 
 |  |  |  |  |  | 
	
		|  D68.69 |  | Other thrombophilia |  
		|  |  | 
| COVID-19 associated hypercoagulability |  | Hypercoagulable states NEC |  | Secondary hypercoagulable state NOS |  
		| CodeAlso | , if applicable, associated condition 
 |  |  |  | 
|  |  | 
	
		|  D68.8 |  | Other specified coagulation defects |  
		|  |  | 
| COVID-19 associated coagulopathy |  
		| CodeAlso | , if applicable, associated condition 
 |  
		| Excludes1 | hemorrhagic disease of newborn (P53) 
 |  |  | 
|  |  | 
	
		|  D68.9 |  | Coagulation defect, unspecified |  |