D68 | 
		  | 
		Other coagulation defects   | 
	
	
		 |  | 
		
	
		| Excludes1 | 
		abnormal coagulation profile NOS (R79.1)
  | 
	 
	
		| Excludes2 | 
		coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)
  | 
	 
 
 | 
	
 |  | 
	
		 D68.0 | 
		  | 
		Von Willebrand disease | 
	 
	
		 |  | 
		
	
		| Excludes1 | 
		capillary fragility (hereditary) (D69.8) factor VIII deficiency NOS (D66) factor VIII deficiency with functional defect (D66)
  | 
	 
 
 | 
	  |  | 
	
		 D68.00 | 
		 | 
		Von Willebrand disease, unspecified | 
	 
  |   |  | 
	
		 D68.01 | 
		  | 
		Von Willebrand disease, type 1 | 
	 
	
		 |  | 
		
| Partial quantitative deficiency of von Willebrand factor |  | Type 1C von Willebrand disease |   
 | 
	   |   |  | 
	
		 D68.02 | 
		  | 
		Von Willebrand disease, type 2 | 
	 
	
		 |  | 
		
| Qualitative defects of von Willebrand factor |   
 | 
	  |  | 
	
		 D68.020 | 
		  | 
		Von Willebrand disease, type 2A | 
	 
	
		 |  | 
		
| Qualitative defects of von Willebrand factor with decreased platelet adhesion and selective deficiency of high-molecular-weight multimers |   
 | 
	   |   |  | 
	
		 D68.021 | 
		  | 
		Von Willebrand disease, type 2B | 
	 
	
		 |  | 
		
| Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss |  | Qualitative defects of von Willebrand factor with hyper-adhesive forms |  | Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb |   
 | 
	   |   |  | 
	
		 D68.022 | 
		  | 
		Von Willebrand disease, type 2M | 
	 
	
		 |  | 
		
| Qualitative defects of von Willebrand factor with defective platelet adhesion with a normal size distribution of von Willebrand factor multimers |   
 | 
	   |   |  | 
	
		 D68.023 | 
		  | 
		Von Willebrand disease, type 2N | 
	 
	
		 |  | 
		
| Qualitative defects of von Willebrand factor with defective von Willebrand factor to factor VIII binding |  | Qualitative defects of von Willebrand factor with markedly decreased affinity for factor VIII |   
 | 
	   |   |  | 
	
		 D68.029 | 
		  | 
		Von Willebrand disease, type 2, unspecified | 
	 
	
		 |  | 
		
| Qualitative defect in von Willebrand factor function, with no further subtyping |   
 | 
	   |    |   |  | 
	
		 D68.03 | 
		  | 
		Von Willebrand disease, type 3 | 
	 
	
		 |  | 
		
| (Near) complete absence of von Willebrand factor |  | Total quantitative deficiency of von Willebrand factor |   
 | 
	   |   |  | 
	
		 D68.04 | 
		  | 
		Acquired von Willebrand disease | 
	 
	
		 |  | 
		
| Acquired von Willebrand syndrome |   
 | 
	   |   |  | 
	
		 D68.09 | 
		  | 
		Other von Willebrand disease | 
	 
	
		 |  | 
		
| Platelet-type von Willebrand disease |  | Pseudo-von Willebrand disease |  	
		| CodeAlso | 
		, if applicable, qualitative platelet defects (D69.1)
  | 
	 
 
 | 
	   |    | 
 |  | 
	
		 D68.1 | 
		  | 
		Hereditary factor XI deficiency | 
	 
	
		 |  | 
		
| Hemophilia C |  | Plasma thromboplastin antecedent [PTA] deficiency |  | Rosenthal's disease |   
 | 
	   | 
 |  | 
	
		 D68.2 | 
		  | 
		Hereditary deficiency of other clotting factors | 
	 
	
		 |  | 
		
| AC globulin deficiency |  | Congenital afibrinogenemia |  | Deficiency of factor I [fibrinogen] |  | Deficiency of factor II [prothrombin] |  | Deficiency of factor V [labile] |  | Deficiency of factor VII [stable] |  | Deficiency of factor X [Stuart-Prower] |  | Deficiency of factor XII [Hageman] |  | Deficiency of factor XIII [fibrin stabilizing] |  | Dysfibrinogenemia (congenital) |  | Hypoproconvertinemia |  | Owren's disease |  | Proaccelerin deficiency |   
 | 
	   | 
 |  | 
	
		 D68.3 | 
		 | 
		Hemorrhagic disorder due to circulating anticoagulants | 
	 
 |  | 
	
		 D68.31 | 
		 | 
		Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors | 
	 
 |  | 
	
		 D68.311 | 
		  | 
		Acquired hemophilia | 
	 
	
		 |  | 
		
| Autoimmune hemophilia |  | Autoimmune inhibitors to clotting factors |  | Secondary hemophilia |   
 | 
	   |   |  | 
	
		 D68.312 | 
		  | 
		Antiphospholipid antibody with hemorrhagic disorder | 
	 
	
		 |  | 
		
| Lupus anticoagulant (LAC) with hemorrhagic disorder |  | Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder |  	
		| Excludes1 | 
		antiphospholipid antibody, finding without diagnosis (R76.0) lupus anticoagulant (LAC) finding without diagnosis (R76.0) systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  | 
	 
	
		| Excludes2 | 
		antiphospholipid antibody syndrome (D68.61) antiphospholipid antibody with hypercoagulable state (D68.61) lupus anticoagulant (LAC) with hypercoagulable state (D68.62) systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62)
  | 
	 
 
 | 
	   |   |  | 
	
		 D68.318 | 
		  | 
		Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors | 
	 
	
		 |  | 
		
| Antithromboplastinemia |  | Antithromboplastinogenemia |  | Hemorrhagic disorder due to intrinsic increase in antithrombin |  | Hemorrhagic disorder due to intrinsic increase in anti-VIIIa |  | Hemorrhagic disorder due to intrinsic increase in anti-IXa |  | Hemorrhagic disorder due to intrinsic increase in anti-XIa |   
 | 
	   |    |   |  | 
	
		 D68.32 | 
		  | 
		Hemorrhagic disorder due to extrinsic circulating anticoagulants | 
	 
	
		 |  | 
		
| Drug-induced hemorrhagic disorder |  | Hemorrhagic disorder due to increase in anti-IIa |  | Hemorrhagic disorder due to increase in anti-Xa |  | Hyperheparinemia |  	
		| UseAdditionalCode | 
		code for adverse effect, if applicable, to identify drug (T45.515, T45.525)
  | 
	 
 
 | 
	   |    | 
 |  | 
	
		 D68.4 | 
		  | 
		Acquired coagulation factor deficiency | 
	 
	
		 |  | 
		
| Deficiency of coagulation factor due to liver disease |  | Deficiency of coagulation factor due to vitamin K deficiency |  	
		| Excludes1 | 
		vitamin K deficiency of newborn (P53)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 D68.5 | 
		  | 
		Primary thrombophilia | 
	 
	
		 |  | 
		
| Primary hypercoagulable states |  	
		| Excludes1 | 
		antiphospholipid syndrome (D68.61) lupus anticoagulant (D68.62) secondary activated protein C resistance (D68.69) secondary antiphospholipid antibody syndrome (D68.69) secondary lupus anticoagulant with hypercoagulable state (D68.69) secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69) systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0) systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312) thrombotic thrombocytopenic purpura (M31.19)
  | 
	 
 
 | 
	  |  | 
	
		 D68.51 | 
		  | 
		Activated protein C resistance | 
	 
	
		 |  | 
		
 | 
	   |   |  | 
	
		 D68.52 | 
		 | 
		Prothrombin gene mutation | 
	 
  |   |  | 
	
		 D68.59 | 
		  | 
		Other primary thrombophilia | 
	 
	
		 |  | 
		
| Antithrombin III deficiency |  | Hypercoagulable state NOS |  | Primary hypercoagulable state NEC |  | Primary thrombophilia NEC |  | Protein C deficiency |  | Protein S deficiency |  | Thrombophilia NOS |   
 | 
	   |    | 
 |  | 
	
		 D68.6 | 
		  | 
		Other thrombophilia | 
	 
	
		 |  | 
		
| Other hypercoagulable states |  	
		| Excludes1 | 
		diffuse or disseminated intravascular coagulation [DIC] (D65) heparin induced thrombocytopenia (HIT) (D75.82-) hyperhomocysteinemia (E72.11)
  | 
	 
 
 | 
	  |  | 
	
		 D68.61 | 
		  | 
		Antiphospholipid syndrome | 
	 
	
		 |  | 
		
| Anticardiolipin syndrome |  | Antiphospholipid antibody syndrome |  	
		| Excludes1 | 
		anti-phospholipid antibody, finding without diagnosis (R76.0)
  | 
	 
	
		| Excludes2 | 
		anti-phospholipid antibody with hemorrhagic disorder (D68.312) lupus anticoagulant syndrome (D68.62)
  | 
	 
 
 | 
	   |   |  | 
	
		 D68.62 | 
		  | 
		Lupus anticoagulant syndrome | 
	 
	
		 |  | 
		
| Lupus anticoagulant |  | Presence of systemic lupus erythematosus [SLE] inhibitor |  	
		| Excludes1 | 
		lupus anticoagulant (LAC) finding without diagnosis (R76.0)
  | 
	 
	
		| Excludes2 | 
		anticardiolipin syndrome (D68.61) antiphospholipid syndrome (D68.61) lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312)
  | 
	 
 
 | 
	   |   |  | 
	
		 D68.69 | 
		  | 
		Other thrombophilia | 
	 
	
		 |  | 
		
| COVID-19 associated hypercoagulability |  | Hypercoagulable states NEC |  | Secondary hypercoagulable state NOS |  	
		| CodeAlso | 
		, if applicable, associated condition
  | 
	 
 
 | 
	   |    | 
 |  | 
	
		 D68.8 | 
		  | 
		Other specified coagulation defects | 
	 
	
		 |  | 
		
| COVID-19 associated coagulopathy |  	
		| CodeAlso | 
		, if applicable, associated condition
  | 
	 
	
		| Excludes1 | 
		hemorrhagic disease of newborn (P53)
  | 
	 
 
 | 
	   | 
 |  | 
	
		 D68.9 | 
		 | 
		Coagulation defect, unspecified | 
	 
  |